Annual report pursuant to Section 13 and 15(d)

Document and Entity Information

Document and Entity Information - USD ($)
$ in Millions
12 Months Ended
Dec. 31, 2021
Mar. 15, 2022
Jun. 30, 2021
Cover [Abstract]      
Document Type 10-K    
Amendment Flag false    
Document Period End Date Dec. 31, 2021    
Document Fiscal Year Focus 2021    
Document Fiscal Period Focus FY    
Entity Registrant Name GRAPHITE BIO, INC.    
Entity Central Index Key 0001815776    
Current Fiscal Year End Date --12-31    
Entity Filer Category Non-accelerated Filer    
Entity Small Business true    
Entity Shell Company false    
Entity Emerging Growth Company true    
Entity Ex Transition Period false    
Entity Well-known Seasoned Issuer No    
Entity Voluntary Filers No    
Entity Current Reporting Status Yes    
Entity Interactive Data Current Yes    
Entity Incorporation State Country Code DE    
Entity Address Address Line1 201 Haskins Way    
Entity Address, Address Line Two Suite 210    
Entity Address City Or Town South San Francisco    
Entity Address State Or Province CA    
Entity Address Postal Zip Code 94080    
City Area Code 650    
Local Phone Number 484-0886    
Entity File Number 001-40532    
Entity Tax Identification Number 84-4867570    
Security12b Title Common Stock, par value $0.00001 per share    
Trading Symbol GRPH    
Security Exchange Name NASDAQ    
Document Annual Report true    
Document Transition Report false    
Entity Public Float     $ 817.4
Entity Common Stock, Shares Outstanding   58,010,823  
Auditor Name Deloitte & Touche LLP    
Auditor Location San Francisco, CA    
Auditor Firm ID 34    
Documents Incorporated by Reference [Text Block]


Portions of the registrant’s Definitive Proxy Statement relating to its 2022 Annual Meeting of Stockholders to be filed hereafter are incorporated by reference into Part III of this Annual Report on Form 10-K where indicated.